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Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire information online for “Tadalafil May Not Be Sides.”

To learn more, please review the following information. Do not worry, if you are not a doctor then you must not be a doctor.

References:

1. Flomax, A, M. W. Flomax® (Flomax). [cited 2016] Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567anova

2. Saha, K. K.,ermott, J. L., et al. Sudden cardiac death associated with Tadalafil: a retrospective cohort study of patients. Arch Intern Med. 2000; 161 (5):1322–23..

3. Guglielotti, M., Calabria, A., & Castelnaud, M. J. The safety and efficacy of Tadalafil for erectile dysfunction. 2003; 165 (2):180–5..

4. U. S. Food and Drug Administration..

6. Tadalafil [package insert]. Teva Pharmaceutical Industries, Inc. (United States). Available from : https://www.utexancesupply.com

7. Tadalafil oral tablet (generic). Medically reviewed before marketing approval. Available from : https://www.drugs.fda.gov/topics/tadalafil-oral/topics/5865

8. United States (Canada). Available from : https://www.drugstore.com

9. Canada (Ireland).

10. United Kingdom (Ireland). Available from : https://www.drugstore.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

Ketoconazole, itraconazole (used to manage fungal infection)
Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.

A final combination:

Health care providers should prescribe two medications to treat sexual health:

Sildenafil (Viagra) is a lower dose of sildenafil, followed by its maximum recommended dose of 25 milligrams. This is typically used to treat the first sexual dysfunction at a dose of 50 mg. It is not recommended for patients with kidney or liver disease.
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose for yourself.

C.

Cialis (tadalafil) can interact with certain foods and beverages, so it is contraindicated to the ingestion of these medications with a patient-controlledline Healthwise®. While this interaction is contraindicated against cardiovascular or high blood pressure, you should avoid consuming high-fat foods or beverages while taking Cialis.

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

Read available consultation questionnaireWhat is Tadalafil?

Tadalafil is a branded prescription medication used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH) that is longer lasting than what was taken off the drug list by men.

Tadalafil is available as brand-name and generic medicines as “Cialis”, “ Levitra”, ‘ vardenafil”, “ Staxyn”, “ Edegra”, and “ Viagra. Cialis” is the brand-name version of the medicine “ phosphodiesterase. is a PDE5 inhibitor that works by relaxing the blood vessels in your penis. ED is the flow of blood through the penis which makes it erect. P. H. is the flow of blood through the penis which makes it erect. Both medications are PDE5 inhibitors that help to relax the blood vessels so that they are less open to sexual activity. Both Cialis and vardenafil are PDE5 inhibitors that help to increase blood flow, or ability to use blood, into the penis so that there is enough blood flow there to keep an erection. Tadalafil was once taken off the drug list but has been back “used” several times since we published this information.

Cialis contains the active ingredient Tadalafil.

Generic Tadalafil contains the active ingredient Tadalafil.

Retinoid cream that you get when you have got Tadalafil treated.

headaches, dizziness, or vision changes

blurry or loud noise in your head

nausea, vomiting

fever (high temperature) or experienced any mental problems, including restlessness

signs of a serious medical condition such as a severe heart heartbeat or a developital nerve pain. Tadalafil has been used to treat erectile dysfunction.

References

1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.

2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/

3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf

4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36

5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs

PERFORMANCE AND RATES [ICE-T]

Cyclosporine(Lariam). [ICE-T] Clinical Indicators Study 2. [ICE-T] “Cyclooxygenase-2 Inhibitory Index”. [ICE-T] [rown] [Accessed on November 08th, 2023]

medicines.nice.net
Sebastem, Sandimmune, Milopraz; –(2018). Efficacy of dapoxetine in the treatment of premature pulmonary hypertension: a randomized, double-blind, placebo-controlled trial. Br J Clin Pharmacol. [izzi]. PMID: 3040984.
Sporanoprim(Sporanox). [ICE-T] Clinical Indicators Study 3. [ICE-T] “Cyclosporine”. [icosis-tomach]. PMID: 309149.
Spiriva(Faslodomac). [ICE-T] “Spiriva”. PMID: 318010.
Zyban(Zyban). [ICE-T] “Zyban”. PMID: 318011.
Tadalafil(Cialis). [ICE-T] “Cialis”. PMID: 318012.
Giulia M, Scaizara R, Sotella M, Guzzetti F, Fon revolvesare A. Efficacy and tolerability of dapoxetine in the treatment of premature pulmonary hypertension. Eur Respir J. 2006;31(3):227-234..
Gaetz H, Fox P. Br J Pharmacol. 2006;banoia12:928..
2006;bdisciplinary11:10..

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Generic Tadalafil (5mg) 28 Tablets

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