Drug-Drug Interactions:Tadalafil+dapoxetine may have interaction with anti-hypertensive (amlodipine, lisinopril, losartan, metoprolol, riociguat), alpha-blockers (tamsulosin), anti-anginal (nitroglycerin), anti-fungal (ketoconazole, itraconazole), antibiotics (erythromycin, clarithromycin), anti-TB (rifampicin), anticonvulsants (phenobarbital, phenytoin, carbamazepine), anti-HIV (ritonavir, saquinavir, nelfinavir), pain-killers (tramadol), anti-depressants (lithium, nefazodone), MAO inhibitor (Isocarboxazid, Phenelzine, Selegiline, and Tranylcypromine).
Drug-Food Interactions:Avoid consumption of alcohol as it may temporarily impair your ability to get an erection. Also, do not take St John's wort plant (a natural remedy to treat depression).
Drug-Disease Interactions:Tadalafil+dapoxetine may have interactions with cardiovascular/heart disease, renal dysfunction (kidney impairment), pulmonary disease, alcoholism, liver disease, seizure disorder, hearing loss, retinitis pigmentosa (loss of vision), and priapism (prolonged erection of the penis).
Judd MC, Sperling E, Bower EE, et al: "Disease interactions of tadalafil with dapoxetine."Avoid consumption of alcohol as it temporarily impair your ability to get an erection.
Tadalafil+dapoxetine may have interactions with cardiovascular/heart disease, renal dysfunction (kidney impairment), pulmonary disease, alcoholism, liver disease, seizure disorder, hearing loss, retinitis pigmentosa (loss of vision), retinal neoplasm (loss of vision), and retinal disorders (neurological adverse effects).
This is not a complete list of drug-drug interactions. Give details of any other drug (including interactions) in your group.This information does not cover all other group C drugs).Copyright © 2009 KPMG-UK.
Kater E, Rangasan KR, Bhaskar K, Pekarela KR, Parida KR, et al: "Tadalafil and dapoxetine co-administration improves erectile dysfunction in men with coronary artery disease."Copyright © KPMG-UK.
Published by Kater, 2009. All rights reserved.
This is a summary of Kater's most recent textbook. Kater's textbook is not for women and children.
Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, primarily used to treat erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). Erectile dysfunction is the inability to keep a hard and erect penis suitable for sexual activity. Benign prostatic hyperplasia, also called prostate enlargement, is the non-cancerous growth of the prostate gland.
Tadalafil contains ‘Tadalafil’, which works by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. Thereby, it helps to treat erectile dysfunction. Tadalafil relaxes the bladder and prostate muscles, thereby reducing enlarged prostate symptoms such as difficulty in urination and urgent need to urinate.
You are advised to take Tadalafil for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as headache, back pain, muscle pain, pain in the legs and arms, nasal congestion, indigestion, and facial flushing. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not take Tadalafil if you are taking nitrates (used to treat angina), riociguat (used to treat pulmonary hypertension) or alpha-blockers; if you have heart problems or stroke, low blood pressure or uncontrolled high blood pressure. Tadalafil is not intended for use in women. Tadalafil may cause dizziness, so drive with caution. Avoid consuming alcohol as it might cause increased dizziness. Tadalafil should not be given to children as safety and effectiveness have not been established. Keep your doctor informed about your health condition and the medicines you are taking to avoid unpleasant side effects.
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View MoreALAN TADALAFIL (Taladafil) 100mg/5ml - WarningsTake with food or milk; do not take with heavy or high-fat meals. Swallow the tablet whole; do not crush or chew it. Excessive intake of alcohol is unlikely to improve your symptoms. Inform your doctor about all other medicines you are taking to avoid any possible interaction.
Avoid taking any other medicines during treatment with Tadalafil, as it may increase the risk of side effects. Talk to your doctor if you are using the medicines for pulmonary hypertension or any other reason.
Tadalafil belongs to the group of medicines called phosphodiesterase type 5 (PDE 5) inhibitors, which work by relaxing the blood vessels in the penis; this allows the blood to flow into the penis when the person is sexually excited. When the person is sexually excited, PDE 5 is responsible for breaking down the drug in your body. This causes the smooth muscle in your penis to relax and allowing the blood to flow into your penis as it is during sexual stimulation.
Tadalafil works by inhibiting the action of PDE5, thus allowing the blood to flow into the penis when the person is sexually excited. This increased flow of blood causes the prostate gland to expand, which improves the ability to get an erection. The increased blood flow allows the PDE5 to help deliver the drug into the penis.
It is recommended that PDE5 inhibitors be taken regularly as they can start working early in treatment and may cause side effects such as headache, nausea and dizziness. Inform your doctor if you experience any of these symptoms during sexual activity. They may adjust your dose as needed.
Patients with erectile dysfunction should not use Tadalafil as it can cause temporary penile shrinkage in some men. If you develop symptoms such as difficulty in getting or keeping an erection, stop taking Tadalafil and seek medical attention.
Consult your doctor if you experience back pain, headache, muscle pain,fd headache,dizziness,fainting, priapism (a long lasting erection); any of these uncommon side effects. Inform your doctor if you experience any dizziness, headache, and heart palpitations.
Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As we mentioned earlier, ED can be caused by various factors, so if you’re experiencing ED, you may want to speak to your doctor first. If you’re experiencing ED, it’s important to know that everything can be treated earlier than you think. That means you should speak to your doctor if you have a history of cardiovascular conditions, such as heart failure or high blood pressure, which can all contribute to ED. That is, you can start treatment with Tadalafil or any other PDE5 inhibitor you might be taking to get the best results from it.
If you have a history of cardiovascular conditions, discuss with your doctor if you’re taking any medications, such as nitrates, to treat chest pain or heart problems, or have liver or kidney problems, which can all affect your ED. That is, if you’re taking Tadalafil with a nitrate medication, you should not have an ED experience without a nitrate experience, which can affect your experience with Tadalafil. That is, if you have a history of heart problems, low blood pressure, or stroke, you should not have an ED experience without a history of these conditions.
If you have a history of heart problems, low blood pressure, or stroke, discuss with your doctor if you have a history of liver or kidney problems, or if you’re taking any other medications. That is, if you have a history of kidney problems, such as a history of gout or a condition that can lower the level of sodium in your blood, or if you have diabetes or if you’re having a blood disorder.
If you have diabetes or if you have diabetes, discuss with your doctor if you’re taking any type of medication, such as a diuretic or alpha-blockers, such as doXick (Orlistat), or other oral antifungal medications, such as itraconazole (Roche), or ritonavir (Norvir), or itraconazole (Norvir), such as ketoconazole (Nizoral), or itraconazole (Ketoconazole), or itraconazole (Ornitro Iqalem), or ritonavir (Noritin), such as ritonavir (Oritin), or oritonavir (Tofranil). That is, if you have a history of seizures, or if you have low blood pressure or if you have diabetes, discuss with your doctor if Tadalafil is the best treatment for ED.
If you have underlying medical conditions that can cause ED, such as heart or liver problems, you should always speak to your doctor if you are taking any form of medications, such as alpha-blockers, such as doxazosin (Cardura), or other oral medications, such as alfuzosin (Uroxatral), or other antifungals such as itraconazole (N stigma), or rimegezole (Riv stigma), or rifampin (Rifadin), such as rifabutin (Mycophenolate), or rifabutin (Rifadin).
Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.
Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.
Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.
If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.
For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:
Follow your doctors instructions carefully based on your specific needs and condition.
If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.
Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.
Read the'medication guide and instructions' for the best results with tadalafil and how to take it. Tadalafil may cause dizziness and blurred vision. Take it exactly as instructed by your doctor or pharmacist. If you are experiencing dizziness,⁴ Make sure to drink plenty of water while taking tadalafil.Taking other medications may interact with tadalafil (and other medications. For example, alpha-blockers and antifungals may also increase dosage).
If you are taking riociguat (Adempas) or nitrates (medicines to treat angina)metics changes.
For treatment of pulmonary hypertension, taken with RE8mg, 10mg, 20mg, and 40mg, take it at the same time every day.
If you miss a dose, take it as soon as you remember. If it is near your time ofossip, your ED symptoms start much later than you should. Swallow your Tadalafil dosage whole. Do not split it or crush it unless advised.
Remember that you are taking this medication to ensure you receive a correct treatment plan, even if you don't notice the effects within a few days. It is not known if tadalafil is safe and effective for daily use for all men.
If you are taking tadalafil generic for ED treatment, your doctor will determine the appropriate dosage of tadalafil citrate medication for you based on your age, medical condition, and whether or not you are using other medications for symptoms of BPH. Tell your doctor about all the medications you take, as well as your medical histories so your doctor can safely change your treatment plan if needed.
Ask your doctor if you have any questions you not understood. What to avoid, side effects are possible. Get medical help right away if you experience side effects such as dizziness, drowsiness, or blurred vision. Some medications may have interactions with tadalafil. Get medical help right away if you are prescribed tadalafil generic or other tadalafil medication.This medication has been approved for use in men in treatment.
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